发明名称 CYANOPYRROLE AS PROGESTERONE RECEPTOR AGONIST
摘要 <P>PROBLEM TO BE SOLVED: To provide a novel cyanopyrrole deriative and a use thereof. <P>SOLUTION: This invention provides the cyanopyrrole deriative or pharmaceutically acceptable salt thereof which can bind to a progesterone receptor of formula 1. The compound treats or inhibits breast cancer, uterus cancer, ovarian cancer, endometrium cancer, or prostate cancer. In the formula 1, T is O, S, or absent; and R<SB POS="POST">1</SB>to R<SB POS="POST">6</SB>are each, independently, hydrogen, alkyl, substituted alkyl, etc. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2011236225(A) 申请公布日期 2011.11.24
申请号 JP20110140568 申请日期 2011.06.24
申请人 WYETH LLC 发明人 COLLINS MARK A;MACKNER VALERIE A;ZHI LIN;JONES TODD K;TEGLEY CHRISTOPHER M;WROBEL JAY E;EDWARDS JAMES P
分类号 C07D403/04;A61K31/40;A61K31/403;A61K31/404;A61K31/4045;A61K31/405;A61K31/536;A61K31/5415;A61P5/34;A61P13/08;A61P15/00;A61P15/14;A61P15/16;A61P15/18;A61P35/00;A61P43/00;C07D413/04 主分类号 C07D403/04
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