| 摘要 |
The present invention relates to a new field of indication for phenoxyacetic acid derivatives of the Formula I (see formula I) wherein X is a chiral carbon atom of R or S; Y is a chiral carbon atom of R or S; R1 is a hydroxy group, a C1-C6-alkoxy group, an aryl- C1-C6-alkoxy group, a primary amino group or a mono- or di (C1-C6-alkyl)amino group; one of the groups R2 and R3 is a hydrogen atom, the other group is a hydrogen atom , a halogen atom, a C1-C6-alkyl group, a trifluoromethyl group or a C1-C6-alkoxy group; and R4 is a halogen atom, a C1-C6-alkyl group, a halo (C1-C6-alkyl) group, a hydroxy group, a C1-C6-alkoxy group, an aryl- C1-C6-alkoxy group, a C1-C6-alkoxy group, a cyano group, a nitro group, an amino group, a mono- or di (C1-C6-alkyl)amino group, a carbamoyl group, a mono- or di (C1-C6-alkyl)carbamoyl group or the group -NHCOR5, where R5 is a hydrogen atom or a C1-C6-alkyl group; or a pharmaceutically acceptable salt thereof. It has now been found that the compounds described are suitable for the preparation of a medicament for treating hyperactive bladder (overactive bladder). Accordingly, by means of these active substances, a method is provided for treating this urological syndrome.
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