| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide novel compounds having an NPY Y5 receptor antagonism. <P>SOLUTION: The compounds shown by Formula (I), pharmaceutically permitted salts thereof, or those solvates are disclosed (wherein R<SP POS="POST">1</SP>, R<SP POS="POST">2</SP>and R<SP POS="POST">3</SP>are each independently hydrogen, (un)substituted alkyl, (un)substituted alkoxy, (un)substituted cycloalkyl, (un)substituted cycloalkenyl, (un)substituted aryl, (un)substituted heteroaryl, (un)substituted heterocyclyl or the like; R<SP POS="POST">1</SP>and R<SP POS="POST">2</SP>may join together with an adjoining nitrogen atom to form (un)substituted nitrogen-containing aromatic heterocyclic ring or (un)substituted nitrogen-containing non-aromatic heterocyclic ring; X is S(O), S(O)<SB POS="POST">2</SB>or C(O); m is an integer of 0-2; Y is S or O; R<SP POS="POST">7</SP>s are each independently halogen or the like; and n is an integer of 0-2). <P>COPYRIGHT: (C)2012,JPO&INPIT |
