发明名称 ULTRAVIOLET PROTECTION COMPOSITION COMPRISING A BLT2 INHIBITOR
摘要 The present invention relates to an ultraviolet protection composition comprising a BLT2 inhibitor, and more particularly, to an ultraviolet protection composition which can be used in skin care formulations, anti-inflammatory agents for the skin, ultraviolet-screening protective formulations for the sking, and the like. According to the present invention, it has been identified that BLT2, which is a cell membrane protein, the ligands thereof, the synthetases thereof, etc. are overexpressed by ultraviolet rays irradiated thereto, and thus induce apoptotic cell death by generating reactive oxygen species and activating MAP kinases. It has also been identified that an inhibitor for inhibiting the expression of said protein can effectively protect the skin, the hair, and the like from ultraviolet rays.
申请公布号 WO2011078590(A3) 申请公布日期 2011.11.17
申请号 WO2010KR09242 申请日期 2010.12.23
申请人 KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION;KIM, JAE HONG;RYU, HO CHEOL 发明人 KIM, JAE HONG;RYU, HO CHEOL
分类号 A61K39/395;A61K31/7105;A61P17/00;A61Q5/00 主分类号 A61K39/395
代理机构 代理人
主权项
地址