| 发明名称 |
MODIFIED CLOSTRIDIAL TOXINS COMPRISING AN INTEGRATED PROTEASE CLEAVAGE SITE-BINDING DOMAIN |
| 摘要 |
The present specification discloses modified Clostridial toxins, compositions comprising an integrated protease cleavage site-binding domain, polynucleotide molecules encoding such modified Clostridial toxins and compositions comprising di-chain forms of such modified Clostridial toxins.
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| 申请公布号 |
CA2784666(A1) |
申请公布日期 |
2011.11.17 |
| 申请号 |
CA20102784666 |
申请日期 |
2010.12.14 |
| 申请人 |
ALLERGAN, INC. |
发明人 |
GHANSHANI, SANJIV;LE, LINH Q.;LIU, YI;STEWARD, LANCE E. |
| 分类号 |
C12N9/64;A61K8/66;A61P29/00;A61Q19/08;C07H21/00;C07K14/33;C12N9/52;C12N15/63 |
主分类号 |
C12N9/64 |
| 代理机构 |
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