| 发明名称 |
Polyphenol proteasome inhibitors, synthesis, and methods of use |
| 摘要 |
The present invention relates to synthetic green tea derived polyphenolic compounds, their modes of syntheses, and their use in inhibiting proteasomal activity and in treating cancers. The present invention is also directed to pharmaceutical compositions useful in methods of inhibiting proteasomes and of treating cancers. |
| 申请公布号 |
US8058310(B2) |
申请公布日期 |
2011.11.15 |
| 申请号 |
US20100660351 |
申请日期 |
2010.02.25 |
| 申请人 |
DOU Q. PING;CHAN TAK-HANG;SMITH DAVID M.;UNIVERSITY OF SOUTH FLORIDA;MCGILL UNIVERSITY;THE HONG KONG POLYTECHNIC UNIVERSITY |
发明人 |
DOU Q. PING;CHAN TAK-HANG;SMITH DAVID M. |
| 分类号 |
A61K31/235;A61K31/16;C07C69/88;C07C235/54;C07D311/60 |
主分类号 |
A61K31/235 |
| 代理机构 |
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