发明名称 |
Modification of protein glycosylation in methylotrophic yeast |
摘要 |
The present invention relates to methods and genetically engineered methylotrophic yeast strains for producing glycoproteins with mammalian-like glycosylation. The present invention also relates to vectors useful for generating methylotrophic yeast strains capable of producing glycoproteins with mammalian-like glycosylation. Glycoproteins produced from the genetically engineered methylotrophic yeast strains are also provided. |
申请公布号 |
US8058053(B2) |
申请公布日期 |
2011.11.15 |
申请号 |
US20090369239 |
申请日期 |
2009.02.11 |
申请人 |
CONTRERAS ROLAND;CALLEWAERT NICO L. M.;VERVECKEN WOUTER;KAIGORODOV VLADIMIR;VIB, VZW;UNIVERSITEIT GENT;RESEARCH CORPORATION TECHNOLOGIES, INC. |
发明人 |
CONTRERAS ROLAND;CALLEWAERT NICO L. M.;VERVECKEN WOUTER;KAIGORODOV VLADIMIR |
分类号 |
C12Q1/68;C12N15/04;C12N15/81;C12P19/18;C12P21/00 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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