发明名称 |
COMPOSITIONS FOR AMELIORATING CELL PROLIFERATIVE DISORDERS AND METHODS OF MAKING AND USING THEM |
摘要 |
<p>In alternative embodiments, the invention provides apratoxin F and apratoxin G compounds, which include apratoxin F and apratoxin G stereoisomers, derivatives and analogs compositions and methods. In alternative embodiments, the invention provides pharmaceutical compositions and formulations comprising apratoxin F (compound 6 of Figure 1) and apratoxin G (compound 7 of Figure 1) and their stereoisomers, derivatives and analogs. In alternative embodiments, pharmaceutical compositions and formulations of the invention are administered in an amount sufficient to treat, prevent and/or ameliorate a disease or condition that can be ameliorated by decreasing or inhibiting cell growth, e.g., pathological, uncontrolled or unwanted cell growth, e.g., a cancer or a metastases, or any disease or condition (e.g., allergy) or infection having a hyperproliferative cell growth component.</p> |
申请公布号 |
WO2011112893(A9) |
申请公布日期 |
2011.11.10 |
申请号 |
WO2011US28029 |
申请日期 |
2011.03.11 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;GERWICK, WILLIAM, H.;TIDGEWELL, KEVIN;VALERIOTE, FRED |
发明人 |
GERWICK, WILLIAM, H.;TIDGEWELL, KEVIN;VALERIOTE, FRED |
分类号 |
A61K31/427;A61K9/08;A61K9/20;A61K31/426;A61P25/00;A61P29/00 |
主分类号 |
A61K31/427 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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