NOVEL KETOLIDE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS THEREOF

摘要

Provided are ketolide derivatives of general formula (I) or (II), or pharmaceutically acceptable salts or esters thereof formed with inorganic acids or organic acids. In the formula, Ar represents aromatic heterocyclic alkyl or substituted aromatic heterocyclic alkyl; and X is hydrogen or fluorine. Preparation methods of the compounds of general formula (I) or (II), pharmaceutical compositions containing the same and their uses as anti-infectious drugs are also provided.