发明名称 |
ENGINEERED E2 FOR INCREASING THE CONTENT OF FREE LYS11-LINKED UBIQUITIN |
摘要 |
The invention provides a chimeric E2 enzyme comprising a Ubc domain fused to a heterologous ubiquitin binding domain (UBD). The chimeric enzymes of the invention are useful in producing elevated levels of free polyubiquitin. |
申请公布号 |
CA2798585(A1) |
申请公布日期 |
2011.11.10 |
申请号 |
CA20112798585 |
申请日期 |
2011.05.06 |
申请人 |
MEDICAL RESEARCH COUNCIL |
发明人 |
KOMANDER, DAVID;BREMM, ANJA |
分类号 |
C07K14/47 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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