TUBBY-LIKE PROTEIN ISOFORMS AND THEIR APPLICATIONS

摘要

Flag tagged TUBBY-like protein isoforms that are recombinantly expressed in cell lines are disclosed. These cell lines are used to identify specific DNA sites that are in direct physical interaction with transcription factors to identify genes responsible for various neurodegenerative diseases. Diagnostic testing and various therapies to treat the genetic diseases are also part of the present invention.