摘要 |
<P>PROBLEM TO BE SOLVED: To provide a botulinum toxin oral formulation having biocompatibility. <P>SOLUTION: The pharmaceutical compositions comprising a botulinum toxin and a carrier for oral administration to a patient. The composition exhibits gastric retention due to delayed gastric emptying by mucoadhesion, flotation, sedimentation, expansion, or a pharmacological agent. <P>COPYRIGHT: (C)2012,JPO&INPIT |