发明名称 Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
摘要 The present invention relates to compounds defined by Formula (I), wherein the groups A, B, X, m, n and o are defined as in claim 1, possessing valuable pharmacological activity. Particularly the compounds are inhibitors of 11&bgr;-hydroxysteroid dehydrogenase (HSD) 1 and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this enzyme, such as metabolic diseases, in particular diabetes type 2, obesity and dyslipidemia.
申请公布号 US2011269791(A1) 申请公布日期 2011.11.03
申请号 US20090991722 申请日期 2009.05.12
申请人 BOEHRINGER INGELHEIM INTERNATIONAL GMBH 发明人 PETERS STEFAN;ECKHARDT MATTHIAS;HAMILTON BRADFORD S.;HIMMELSBACH FRANK;KLEY JOERG;LEHMANN-LINTZ THORSTEN
分类号 A61K31/439;A61K31/397;A61K31/4985;A61P3/00;A61P3/06;A61P3/10;C07D221/26;C07D471/04 主分类号 A61K31/439
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