| 发明名称 |
COMPOSITIONS AND METHODS FOR DELIVERING A SUBSTANCE TO A BIOLOGICAL TARGET |
| 摘要 |
The present application provides compositions and methods using bioorthogonal inverse electron demand Diels-Alder cycloaddition reaction for rapid and specific covalent delivery of a “payload” to a ligand bound to a biological target.
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| 申请公布号 |
US2011268654(A1) |
申请公布日期 |
2011.11.03 |
| 申请号 |
US200913126660 |
申请日期 |
2009.11.02 |
| 申请人 |
THE GENERAL HOSPITAL CORPORATION |
发明人 |
HILDERBRAND SCOTT A.;DEVARAJ NEAL K.;WEISSLEDER RALPH |
| 分类号 |
A61K51/00;A61K31/337;A61K31/407;A61K31/473;A61K31/4745;A61K31/7048;A61K31/713;A61K38/10;A61K49/00;A61K49/04;A61K49/06;A61K49/22;A61P31/00;B82Y5/00;C12N5/071;C12Q1/02 |
主分类号 |
A61K51/00 |
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