Modulation of the immune system by inositol phospholipids

摘要

The invention relates to the field of immunology. More specifically, it relates to methods and compositions to suppress the immune system, among other by interference with antigen-presenting molecules and T-cell activation. Provided is a composition for the prevention or treatment of a condition wherein suppression of T cell activation is desirable, comprising as an active ingredient an inositol phospholipid or a pharmaceutically acceptable salt thereof wherein the inositol phispholipid is a diacylglycerol phosphotidyl inositol. Said condition can be an auto-immune disease, for example psoriasis.