发明名称 |
ANTI-TRAIL-R ANTIBODIES |
摘要 |
Anti-TRAIL-R1 and R2 antibodies or functional fragments thereof, having at least one property selected from the following (a) to (c) of: (a) having activity to induce apoptosis in carcinoma cells expressing TRAIL-R1 and/or TRAIL-R2; (b) not having effect on normal human cells expressing TRAIL-R1 and/or TRAIL-R2; and (c) not inducing human hepatocyte toxicity.
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申请公布号 |
CA2447602(C) |
申请公布日期 |
2011.11.01 |
申请号 |
CA20022447602 |
申请日期 |
2002.05.17 |
申请人 |
KIRIN BEER KABUSHIKI KAISHA |
发明人 |
MORI, EIJI;KATAOKA, SHIRO |
分类号 |
C07K16/28;A61K39/395;C12N1/19;C12N1/21;C12N5/10;C12N15/13;C12P21/08 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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