发明名称 SYSTEM AND METHOD FOR THE LARGE SCALE LABELING OF COMPOUNDS WITH RADIOHALOGENS
摘要 The invention relates to a new method for producing radio-halogenated compounds having very high specific radioactivity. The method improves the stability of the radio-labeled compound such that its biological and/or chemical activity is retained. The main aspect of the invention is that vitamin C and/or ethanol is added to the radiolabeled compound at either or both of just following attachment of the radio-halogen and during purification of the radio-halogenated compound from the labeling mixture, or during packaging for storage.
申请公布号 CA2450231(C) 申请公布日期 2011.11.01
申请号 CA20022450231 申请日期 2002.06.25
申请人 THE UNIVERSITY OF TORONTO;THE UNIVERSITY OF ALBERTA, THE UNIVERSITY OF BRITISH COLUMBIA, CARLETON UNIVERSITY, SIMON FRASER UNIVERSITY;THE UNIVERSITY OF VICTORIA, COLLECTIVELY DOING BUSINESS AS TRIUMF 发明人 LU, JIANMING
分类号 A61K51/08;C07H19/073;A61K51/04;A61K51/10;C07B59/00;C07H19/06;C07J1/00;C07J7/00;C07J75/00;C07K1/13;C07K1/16;C07K16/00;C07K16/26;G01N33/534 主分类号 A61K51/08
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