Novel pyrrolidone derivatives for use as MetAP-2 inhibitors
摘要
Compounds of the formula (I), in which R, X, Y, Z, R3 and R4 have the meanings indicated in claim 1, are inhibitors of methionine aminopeptidase and can be employed for the treatment of tumours.
申请公布号
US2011263561(A1)
申请公布日期
2011.10.27
申请号
US20090996786
申请日期
2009.05.13
申请人
MERCK PATENT GMBH
发明人
HEINRICH TIMO;KRIER MIREILLE;KNOECHEL THORSTEN;JONCZYK ALFRED;ZENKE FRANK;ENDERLE HOLGER