发明名称 Novel pyrrolidone derivatives for use as MetAP-2 inhibitors
摘要 Compounds of the formula (I), in which R, X, Y, Z, R3 and R4 have the meanings indicated in claim 1, are inhibitors of methionine aminopeptidase and can be employed for the treatment of tumours.
申请公布号 US2011263561(A1) 申请公布日期 2011.10.27
申请号 US20090996786 申请日期 2009.05.13
申请人 MERCK PATENT GMBH 发明人 HEINRICH TIMO;KRIER MIREILLE;KNOECHEL THORSTEN;JONCZYK ALFRED;ZENKE FRANK;ENDERLE HOLGER
分类号 A61K31/519;A61K31/52;A61K31/5377;A61P3/04;A61P3/10;A61P9/10;A61P17/06;A61P19/02;A61P19/10;A61P27/02;A61P35/00;A61P35/02;A61P35/04;C07D403/04;C07D403/14;C07D413/14 主分类号 A61K31/519
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