| 发明名称 |
1-(2-FLUOROBIPHENYL-4-YL)-ALKYL CARBOXYLIC ACID DERIVATIVES FOR THE THERAPY OF TRANSTHYRETIN AMYLOIDOSIS |
| 摘要 |
Derivatives of 1-(2-fluorobiphenyl-4-yl)-alkyl carboxylic acid are capable of stabilizing the tetrameric native state of transthyretin for the prophylaxis and treatment of amyloidosis.
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| 申请公布号 |
US2011263711(A1) |
申请公布日期 |
2011.10.27 |
| 申请号 |
US201113091195 |
申请日期 |
2011.04.21 |
| 申请人 |
CHIESI FARMACEUTICI S.P.A. |
发明人 |
IMBIMBO BRUNO PIETRO;VILLETTI GINO;BERNI RODOLFO |
| 分类号 |
A61K31/192;A61P9/00;A61P13/12;A61P21/00;A61P25/00 |
主分类号 |
A61K31/192 |
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