发明名称 MOLECULAR MARKER FOR CANCER STEM CELL
摘要 A molecular marker for detecting a cancer stem cell in a cell mass which is a subject of interest, wherein the molecular marker can be detected in a cancer stem cell contained in the subject of interest but cannot be detected in a normal cell and a cancer cell that is different from a cancer stem cell; a method for determining the presence or absence of a cancer stem cell in a subject of interest by using the molecular marker as an measure; a kit for determining the presence or absence of a cancer stem cell, which comprises at least a reagent for detecting the molecular marker; a polypeptide encoded by the molecular marker; an antibody capable of recognizing an epitope of an expression product of a gene derived from the molecular marker; a nucleic acid capable of inhibiting the expression of the molecular marker; and a nucleic acid vaccine comprising a gene derived from the molecular marker.
申请公布号 US2011262358(A1) 申请公布日期 2011.10.27
申请号 US200913126039 申请日期 2009.10.27
申请人 SAPPORO MEDICAL UNIVERSITY;DAINIPPON SUMITOMO PHARMA CO., LTD. 发明人 TORIGOE TOSHIHIKO;HIROHASHI YOSHIHIKO;SATOH NORIYUKI;KAMIGUCHI KENJIRO;MORITA RENA;NISHIZAWA SATOSHI;TAKAHASHI AKARI
分类号 A61K49/00;A61K31/7088;A61K38/02;A61K39/00;A61K39/395;A61P35/00;A61P43/00;C07H21/00;C07H21/02;C07H21/04;C07K7/00;C07K16/18;C12N5/095;C12Q1/02;C12Q1/04;C12Q1/48;C12Q1/68;G01N33/566 主分类号 A61K49/00
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