发明名称 |
MOLECULAR MARKER FOR CANCER STEM CELL |
摘要 |
A molecular marker for detecting a cancer stem cell in a cell mass which is a subject of interest, wherein the molecular marker can be detected in a cancer stem cell contained in the subject of interest but cannot be detected in a normal cell and a cancer cell that is different from a cancer stem cell; a method for determining the presence or absence of a cancer stem cell in a subject of interest by using the molecular marker as an measure; a kit for determining the presence or absence of a cancer stem cell, which comprises at least a reagent for detecting the molecular marker; a polypeptide encoded by the molecular marker; an antibody capable of recognizing an epitope of an expression product of a gene derived from the molecular marker; a nucleic acid capable of inhibiting the expression of the molecular marker; and a nucleic acid vaccine comprising a gene derived from the molecular marker. |
申请公布号 |
US2011262358(A1) |
申请公布日期 |
2011.10.27 |
申请号 |
US200913126039 |
申请日期 |
2009.10.27 |
申请人 |
SAPPORO MEDICAL UNIVERSITY;DAINIPPON SUMITOMO PHARMA CO., LTD. |
发明人 |
TORIGOE TOSHIHIKO;HIROHASHI YOSHIHIKO;SATOH NORIYUKI;KAMIGUCHI KENJIRO;MORITA RENA;NISHIZAWA SATOSHI;TAKAHASHI AKARI |
分类号 |
A61K49/00;A61K31/7088;A61K38/02;A61K39/00;A61K39/395;A61P35/00;A61P43/00;C07H21/00;C07H21/02;C07H21/04;C07K7/00;C07K16/18;C12N5/095;C12Q1/02;C12Q1/04;C12Q1/48;C12Q1/68;G01N33/566 |
主分类号 |
A61K49/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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