发明名称 PYRIDONE AND PYRIDAZONE ANALOGUES AS GPR119 MODULATORS
摘要 Novel compounds of structure Formula (I) or an enantiomer, a diastereomer, or a pharmaceutically acceptable salt thereof, wherein Z, R1, R2, R21, T1, T2, T3 and T4 are defined herein, are provided which are GPR119 G protein-coupled receptor modulators. GPR119 G protein-coupled receptor modulators are useful in treating, preventing, or slowing the progression of diseases requiring GPR119 G protein-coupled receptor modulator therapy. Thus, the disclosure also concerns compositions comprising these novel compounds and methods of treating diseases or conditions related to the activity of the GPR119 G protein-coupled receptor by using any of these novel compounds or a composition comprising any of such novel compounds.
申请公布号 US2011263548(A1) 申请公布日期 2011.10.27
申请号 US200913003914 申请日期 2009.07.15
申请人 BRISTOL-MYERS SQUIBB COMPANY 发明人 WACKER DEAN A.;ROSSI KAREN A.;WANG YING;WU GANG
分类号 A61K31/573;A61K31/4545;A61K31/501;A61K31/506;A61P3/04;A61P3/10;A61P9/10;A61P9/12;A61P25/00;A61P25/28;A61P31/00;A61P35/00;C07D401/12;C07D401/14 主分类号 A61K31/573
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