发明名称 MMP-2 AND/OR MMP-9 INHIBITOR
摘要 The present invention provides a highly safe pharmaceutical preparation effective for diseases caused by MMP-2 and/or MMP-9. The pharmaceutical preparation contains, as an active ingredient, at least one member selected from the group consisting of thiazole derivatives represented by Formula (1): wherein R1 represents a phenyl group that may have 1 to 3 lower alkoxy groups as substituents on the phenyl ring, and R2 represents a pyridyl group that may have 1 to 3 carboxyl groups as substituents on the pyridine ring, and salts thereof. Such thiazole derivatives have MMP-2 and/or MMP-9 inhibitory activity.
申请公布号 ZA201005991(B) 申请公布日期 2011.10.26
申请号 ZA20100005991 申请日期 2010.08.23
申请人 OTSUKA PHARMACEUTICAL CO LTD 发明人 MINATOGUCHI SHINYA;OHNO YASUSHI;YABUUCHI YOUICHI;KOTOSAI KOUNORI;NAGAMOTO HISASHI
分类号 A61K;A61P 主分类号 A61K
代理机构 代理人
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