PROCESS FOR DEUTERATION OR TRITIATION OF SACCHARIDE

摘要

A process for the deuteration or tritiation of a saccharide, characterized in that a saccharide which contains a furanose or pyranose constituent component wherein no hydroxyl group is bonded to any carbon atom bonded to the oxygen atom of the tetrahydrofuran or teterahydropyran ring and a hydroxyl group is bonded to at least one of the other carbon atoms is reacted with a deuterated or tritiated solvent in the presence of a ruthenium catalyst and hydrogen gas to replace selectively a hydrogen atom bonded to the carbon atom which a hydroxyl group is directly bonded to by a deuterium or tritium atom.