发明名称 Pyrazine-2-carboxamide derivatives to treat diseases mediated by blockade of the epithelial sodium channel
摘要 A compound of Formula I in free or salt or solvate form, where R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and R11 have the meanings as indicated in the specification, is useful for treating diseases which respond to the blockade of the epithelial sodium channel. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
申请公布号 US8039472(B2) 申请公布日期 2011.10.18
申请号 US20080332086 申请日期 2008.12.10
申请人 NOVARTIS AG 发明人 BHALAY GURDIP;BUDD EMMA;BLOOMFIELD GRAHAM CHARLES;COLLINGWOOD STEPHEN PAUL;DUNSTAN ANDREW;EDWARDS LEE;GEDECK PETER;HOWSHAM CATHERINE;HUNT PETER;HUNT THOMAS ANTHONY;OAKLEY PAUL;SMITH NICHOLA
分类号 A61K31/497;A61K31/50;C07D237/00 主分类号 A61K31/497
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