| 发明名称 |
BENZYLIMIDAZOLYL SUBSTITUTED 2-QUINOLINE AND QUINAZOLINE DERIVATIVES FOR USE AS FARNESYL TRANSFERASE INHIBITORS |
| 摘要 |
This invention comprises the novel compounds of formula (I) wherein r, t, Y1, Y2, R1, R2, R3, R5, R6 and R7 have defined meanings, having farnesyl transferase inhibiting activity; their preparation, compositions containing them and their use as a medicine to treat e.g. cancer.
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| 申请公布号 |
CA2478813(C) |
申请公布日期 |
2011.10.18 |
| 申请号 |
CA20032478813 |
申请日期 |
2003.03.18 |
| 申请人 |
JANSSEN PHARMACEUTICA N.V. |
发明人 |
ANGIBAUD, PATRICK RENE;VENET, MARC GASTON;MEYER, CHRISTOPHE;BRESLIN, HENRY JOSEPH |
| 分类号 |
C07D471/04;A61K31/4178;A61K31/4704;A61K31/4709;A61K31/4745;A61P1/00;A61P1/04;A61P3/04;A61P3/10;A61P5/00;A61P9/00;A61P9/10;A61P9/12;A61P11/00;A61P11/02;A61P11/06;A61P13/12;A61P15/00;A61P17/00;A61P17/04;A61P17/08;A61P17/14;A61P19/02;A61P19/06;A61P19/08;A61P25/00;A61P25/02;A61P25/28;A61P27/02;A61P29/00;A61P31/04;A61P31/12;A61P31/18;A61P33/06;A61P35/00;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07D401/06;C07D401/14;C07D403/06;C07D487/04 |
主分类号 |
C07D471/04 |
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