发明名称 COMPOSITION AND METHOD FOR REDUCING RISK OF EPILEPTIC OCCURRENCE AND/OR FOR TREATMENT OF SEIZURE DISORDER
摘要 PROBLEM TO BE SOLVED: To provide the compounds useful for reducing the risk of epileptic occurrences and/or for alleviating epileptic phenomena in patients, and to provide the compositions including the compounds.SOLUTION: There are provided the compounds in which at least the following two components are chemically bonded, and compositions comprising the compounds: (a) vitamin B6-based component selected from pyridoxal, pyridoxamine, pyridoxine, their pharmaceutically acceptable functional derivatives and salts; and (b) at least one antiepileptic drug (AED) or anticonvulsive, neuroprotective drug or neurotropic compound or moiety. Further, epileptic episodes is prevented and alleviated by using the above compounds, and the side effects of antiepileptic drugs can be reduced.
申请公布号 JP2011201910(A) 申请公布日期 2011.10.13
申请号 JP20110122141 申请日期 2011.05.31
申请人 D-PHARM LTD;ADVANCED NEUROPROTECTIVE SYSTEMS LTD 发明人 DOLINA SVETLANA;SHTEIMAN VITALY;VINNIKOVA MARINA;SHAPIRO ISRAEL
分类号 C07D213/66;A61K;A61K31/44;A61K31/4415;A61K31/4439;A61K31/4709;A61K31/513;A61K31/515;A61P25/08;C07D;C07D213/02;C07D401/12;C07D403/12 主分类号 C07D213/66
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