发明名称 |
IBUPROFEN FOR TOPICAL ADMINISTRATION |
摘要 |
Set forth herein is a preparation of ibuprofen (2-(4-isobutylphenyl)propionic acid) in the free acid form that is suitable for topical administration. The topical ibuprofen formulation is prepared by dissolving the free acid form of ibuprofen, or preparing a homogeneous suspension of the free acid form of ibuprofen, in the presence of a pharmaceutically acceptable solvent so as to produce a topical drug formulation compatible with the penetration of 2-(4-isobutylphenyl) propionic acid through the skin tissue. Topical formulations of ibuprofen can be based on a pharmaceutically acceptable solvent such as, e.g., a pyrrolidone solvent or dimethylacetamide. |
申请公布号 |
EP2373346(A2) |
申请公布日期 |
2011.10.12 |
申请号 |
EP20090792433 |
申请日期 |
2009.09.10 |
申请人 |
BIOCHEMICS, INC. |
发明人 |
CARTER, STEPHEN, G.;ZHU, ZHEN;PATEL, KANU;KOZWICH, DIANE |
分类号 |
A61K47/32 |
主分类号 |
A61K47/32 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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