发明名称 8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine, its salts, solvates or hydrates and its use for the treatment of CNS disorders
摘要 The present relation relates to 8-chloro-1-methyl-2,3,4,5-tetrahydro-1 H -3-benzazepine or a pharmaceutically acceptable salt, solvate, or hydrate thereof for the treatment of a disorder of the central nervous system selected from: depression, atypical depression, a bipolar disorder, an anxiety disorder, an obsessive-compulsive disorder, a social phobia, a panic state, a sleep disorder, sexual dysfunction, psychosis, schizophrenia, migrane or other condition associated with cephalic pain or other pain, raised intracranial pressure, epilepsy, a personality disorder, an age-related behavioral disorder, a behavioral disorder associated with dementia, an organic mental disorder, a mental disorder in childhood, aggressivity, an age-related mental disorder, chronic fatigue syndrome, drug addiction, alcohol addiction, bulimia, anorexia nervosa, or premenstrual tension.
申请公布号 EP2374796(A1) 申请公布日期 2011.10.12
申请号 EP20100010297 申请日期 2003.04.11
申请人 ARENA PHARMACEUTICALS, INC. 发明人 SMITH, JEFFREY;SMITH, BRIAN
分类号 C07D223/14;C07D223/16;A61K31/55;A61P1/00;A61P3/00;A61P3/04;A61P9/00;A61P11/00;A61P13/02;A61P15/00;A61P25/00;A61P25/04;A61P25/06;A61P25/08;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/30;A61P25/32;A61P43/00;C07D223/32;C07D403/04;C07D409/04;C07D487/00;C07D491/00;C07D491/04;C07D491/048;C07D513/00 主分类号 C07D223/14
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