发明名称 |
Recombinant antibodies against CD55 and CD59 and uses thereof |
摘要 |
The present invention relates to recombinant antibody molecules and functional fragments thereof, useful for neutralizing the complement regulatory proteins CD55 and CD59, compositions comprising the recombinant molecules and methods of using the recombinant molecules for controlling complement resistance in cancer. The present invention further relates to heterodimeric diabody molecules comprising variable regions specific for CD55/CD59 and CD20.
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申请公布号 |
US8034902(B2) |
申请公布日期 |
2011.10.11 |
申请号 |
US20060919816 |
申请日期 |
2006.05.01 |
申请人 |
QUARK PHARMACEUTICALS, INC. |
发明人 |
MARZARI ROBERTO;SBLATTERO DANIELE;TEDESCO FRANCESCO |
分类号 |
C07K16/00;C12P21/08 |
主分类号 |
C07K16/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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