| 发明名称 |
Gyrase inhibitors and uses thereof |
| 摘要 |
The present invention relates to compounds that inhibit bacterial gyrase and/or Topo IV and pharmaceutically acceptable compositions comprising said compounds. These compounds, and compositions thereof, are useful in treating bacterial infection. Accordingly, the present invention also relates to methods for treating bacterial infections in mammals.
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| 申请公布号 |
US8034832(B2) |
申请公布日期 |
2011.10.11 |
| 申请号 |
US20090478372 |
申请日期 |
2009.06.04 |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
CHARIFSON PAUL;DEININGER DAVID;GRILLOT ANNE-LAURE;LIAO YUSHENG;RONKIN STEVEN;STAMOS DEAN;PEROLA EMANUELE;WANG TIANSHENG;LETIRAN ARNAUD;DRUMM JOSEPH |
| 分类号 |
C07D401/00;A61K31/4439;A61K31/506;A61P31/04;A61P31/06;C07D401/14;C07D403/04;C07D403/14;C07D405/04;C07D405/14;C07D413/14;C07D417/14;C07D471/04;C07D487/04;C07D491/04 |
主分类号 |
C07D401/00 |
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