发明名称 |
Peptide vaccine for inducing the production of anti-amyloidβ-peptide antibody |
摘要 |
An object of the present invention is to provide a peptide vaccine for preventing and/or treating diseases caused by amyloid &bgr;-peptide, such as Alzheimer's disease. The present invention solves the above object by providing a peptide vaccine constructed by inserting a peptide having an amino acid sequence of a cell attachment motif of a cell adhesive molecule to a peptide which consists of a peptide having an amino acid sequence of multiagretope type T-cell epitope, which has been generated immunological memory, or a peptide including the same; an linker peptide; and a peptide having an amino acid sequence of a B cell epitope which is a specific region of amyloid &bgr;-peptide or a peptide including the same.
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申请公布号 |
US8034353(B2) |
申请公布日期 |
2011.10.11 |
申请号 |
US20070280535 |
申请日期 |
2007.02.16 |
申请人 |
KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO |
发明人 |
YANO AKIRA;NISHIZAWA TOSHIKI;MIWA YOSHIKATSU |
分类号 |
A61K39/02;A61K39/04;A61K39/05;A61K39/08;C07H21/04 |
主分类号 |
A61K39/02 |
代理机构 |
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主权项 |
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地址 |
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