| 发明名称 |
ASSESSMENT OF SUBCHONDRAL BONE REMODELLING BY MEASURING CATHEPSIN K FRAGMENTS OF COLLAGEN TYPE II |
| 摘要 |
A method of assay to determine the extent of collagen type II resorption activity comprising measuring the level of fragments of collagen type II that contain a cathepsin K generated neo-epitope not shared by collagen type I by binding the neo-epitope with an antibody specific for the neo-epitope and detecting the level of binding of said binding partner.
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| 申请公布号 |
US2011244482(A1) |
申请公布日期 |
2011.10.06 |
| 申请号 |
US200913128929 |
申请日期 |
2009.11.11 |
| 申请人 |
NORDIC BIOSCIENCE A/S |
发明人 |
LEEMING DIANA J.;BYRJALSEN INGER;QVIST PER;KARSDAL MORTEN A. |
| 分类号 |
G01N33/566;C07K16/18 |
主分类号 |
G01N33/566 |
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