| 摘要 |
An issue is to prevent a rise in a methemoglobinizing rate of a blend after thawing, in a freeze-preservation method after removing plasma, leucocytes, and blood platelets from red-blood concentrate when extracting to purify hemoglobin material of an artificial oxygen carrier of a hemoglobin base from red-blood concentrate. Disclosed is a hemoglobin material intermediate product used in artificial oxygen carrier manufacturing of a hemoglobin base, characterized in that pH is 7.1 - 7.5 in a thawed solution after freeze-preservation of red blood cells attained by cleaning to remove plasma, leucocytes and blood platelets using an isotonic cleaning solution that contains a pH adjuster, from red-blood concentrate.
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