Protein A Production and Purification without Using Animal Derived Components involving staphylococcus aureus

摘要

Disclosed is a method for producing vegetarian Protein A, free of animal-derived product by: I. fermenting a secretor strain of Staphylococcus aureus (S. aureus) in a media containing vegetarian amino acids or peptides, said media being free of animal products, to produce Protein A; II. harvesting the Protein A-containing media; and III. purifying the Protein A by applying the Protein A-containing media to a synthetic chromatography resin lacking animal products and eluting the Protein A from the resin.