Polycyclic indazole derivatives that are ERK inhibitors

摘要

Disclosed is an indazole of formula 1.0 or the pharmaceutically acceptable salts thereof, wherein the substituents are defined the specification e.g. 1-{ 2-oxo-2-[4-(4-pyrimidin-2-yl-phenyl)-piperazin-1-yl]-ethy1} -pyrrolidine-3-carboxylic acid [3-(1H-imidazol-4-y1)-1H-indazol-5-y1]-amide for treating cancer.