摘要 |
This invention relates to the field of therapeutics. Most specifically, the invention provides methods of generating conditionally expressing vectors for one or more immunomodulators under the control of a gene expression modulation system in the presence of activating ligand and uses for therapeutic purposes in animals. These vector may be provided to treat a variety of disorders, e.g., neoplastic disorders, through direct injection or through in vitro engineered cells, such as dendritic cells. |
申请人 |
ROETH, JEREMIAH F.;REED, CHARLES C.;CUTHBERTSON, BRANDON;CHADA, SUNIL;FOGLER, WILLIAM E. |
发明人 |
ROETH, JEREMIAH F.;REED, CHARLES C.;CUTHBERTSON, BRANDON;CHADA, SUNIL;FOGLER, WILLIAM E. |