ANTENNARY FUCOSYLATION IN GLYCOPROTEINS FROM CHO CELLS

摘要

The present invention provides methods of evaluating CHO cells and producing recombinant glycoproteins. The method of evaluating CHO cells is carried out providing one or more CHO cells from the population and measuring glycans containing antennary fucose residues produced by said cells, wherin the CHO cells have not been genetically engineered to express an alpha 3 / alpha 4 antennary fucosyl - transferase coding sequence.