发明名称 |
MEANS AND METHODS FOR COUNTERACTING, PREVENTING AND/OR DETERMINING HEART FAILURE, OR A RISK OF HEART FAILURE |
摘要 |
The present invention relates to a method for diagnosing and/or prognosing heart failure in a subject the method comprising the step of determining the level of at least one genetic marker in a body fluid sample obtained from said subject, wherein said at least one genetic marker is an mi RNA. The invention further relates to a method for treating or preventing heart failure in a subject the method comprising the step of decreasing within said subject the expression, amount, and/or activity of at least one mi RNA, or decreasing within said subject the interaction of at least one mi RNA with its m RNA target or increasing within said subject the expression, amount, and/or activity of the m RNA target of at least one mi RNA. |
申请公布号 |
WO2010126370(A3) |
申请公布日期 |
2011.09.29 |
申请号 |
WO2010NL50251 |
申请日期 |
2010.04.29 |
申请人 |
ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM;CREEMERS, ESTHER ELISA JOHANNA MARIA;PINTO, YIGAL-MARTIN;TIJSEN, ANKE JOHANNA MARINA |
发明人 |
CREEMERS, ESTHER ELISA JOHANNA MARIA;PINTO, YIGAL-MARTIN;TIJSEN, ANKE JOHANNA MARINA |
分类号 |
C12Q1/68;A61K31/7105;C12N15/113 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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