发明名称 |
Adenovirus derived helper virus for enhancing recombinant parvovirus production |
摘要 |
Described is an adenovirus derived helper virus comprising the adenoviral DNA sequences for E2a, E4(orf6), the VAI RNA gene, and the parvovirus VP capsid gene unit. Also described is a method of efficiently preparing a recombinant parvovirus (particle) which is based on the use of various adenoviral derived helper viruses/vectors. |
申请公布号 |
EP2368903(A1) |
申请公布日期 |
2011.09.28 |
申请号 |
EP20100003296 |
申请日期 |
2010.03.26 |
申请人 |
DEUTSCHES KREBSFORSCHUNGSZENTRUM |
发明人 |
EL-ANDALOUSSI, NAZIM;MARCHINI, ANTONIO;ROMMELAERE, JEAN;LEUCHS, BARBARA;ENDELE, MAX |
分类号 |
C07K14/015;A61K35/00;A61K48/00;C12N15/86;C12N15/864 |
主分类号 |
C07K14/015 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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