发明名称 |
SODIUM-IODIDE SYMPORTER GENE REPRESSOR BINDING SITE |
摘要 |
The present disclosure relates to a sodium iodide symporter (NIS)-repressor binding sites (NRBS) consensus sequence consisting of a DNA molecule having the sequence 5′-T/C(G/A)GCCT(T/C)A(G/A)TTTCCCCA(T/C)CTGT-3′(the “consensus NRBS”). The disclosure further relates to methods of restoring iodide transport in dedifferentiated thyroid cancer cells by interfering with formation or function of the NIS repressor.
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申请公布号 |
US2011229408(A1) |
申请公布日期 |
2011.09.22 |
申请号 |
US20100724898 |
申请日期 |
2010.03.16 |
申请人 |
AIN KENNETH;LI WEI |
发明人 |
AIN KENNETH;LI WEI |
分类号 |
A61K51/00;A61K31/435;A61P35/00;C07H21/00;C12Q1/68 |
主分类号 |
A61K51/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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