<p>Provided is a method of determining the level of resistance or sensitivity of cancer stem cells to a death receptor agonist. The method includes detecting the level of IAP in one or more DR5/DDX3/IAP complexes in or from the cancer stem cells. Also provided is a method of killing cancer stem cells in a subject and a method of reducing the risk of cancer recurrence in a subject.</p>
申请公布号
WO2011116344(A2)
申请公布日期
2011.09.22
申请号
WO2011US29081
申请日期
2011.03.18
申请人
THE UAB RESEARCH FOUNDATION;BUCHSBAUM, DONALD J.;LOBUGLIO, ALBERT F.;ZHOU, TONG
发明人
BUCHSBAUM, DONALD J.;LOBUGLIO, ALBERT F.;ZHOU, TONG