摘要 |
An external patch capable of stable prolonged release and transdermal absorption of active ingredient hormones (estrogens and/or progestogens) contained in a pressure sensitive adhesive layer, which external patch ensures low irritation on the skin. In particular, an external patch comprising a support and, superimposed thereon, a pressure sensitive adhesive layer, characterized in that the pressure sensitive adhesive layer comprises, as indispensable components, 5 to 50 wt.% of styrene/isoprene/styrene block copolymer, 20 to 70 wt.% of tackifier resin, 10 to 60 wt.% of softener and 1 to 20 wt.% of polyvinylpyrrolidone and contains, as an active ingredient, estrogen and/or progestogen.
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申请人 |
TEIKOKU SEIYAKU CO., LTD.;FUSO PHARMACEUTICAL INDUSTRIES, LTD. |
发明人 |
MATSUSHITA, KUNIHIKO;HATTORI, KENICHI;YAMAJI, MASAHIRO |