| 发明名称 |
RECOMBINANT BOVINE PANCREATIC DESOXYRIBONUCLEASE I WITH HIGH SPECIFIC ACTIVITY |
| 摘要 |
A method is provided for the production of a bovine pancreatic protein with a specific desoxyribonuclease activity of at least 6,000 units per mg of protein. Methylotroghic yeast is used as a heterologous host organism. The bovine pancreatic protein is secreted into the growth medium from which it is purified. |
| 申请公布号 |
CA2453948(C) |
申请公布日期 |
2011.09.20 |
| 申请号 |
CA20032453948 |
申请日期 |
2003.12.18 |
| 申请人 |
F.HOFFMANN-LA ROCHE AG |
发明人 |
MUELLER, RAINER;SUPPMANN, BERNHARD;THALHOFER, JOHANN-PETER;RONNING, STEPHANIE;SCHOEN, HELMUT |
| 分类号 |
C12N15/09;C12N15/55;C12N9/22;C12N9/88;C12N15/81;C12P19/34;C12R1/72 |
主分类号 |
C12N15/09 |
| 代理机构 |
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