发明名称 |
THE USE OF FENOTEROL AND FENOTEROL ANALOGUES IN THE TREATMENT OF GLIOBLASTOMAS AND ASTROCYTOMAS |
摘要 |
This disclosure concerns the discovery of the use of fenoterol and (R, R)- and (R, S)- fenoterol analogues for the treatment of a tumor expressing a ß2-adrenergic receptor, such as a primary brain tumor, including a glioblastoma or astrocytoma expressing a ß2- adrenergic receptor. In one example, the method includes administering to a subject a therapeutically effective amount of fenoterol, a specific fenoterol analogue or a combination thereof to reduce one or more symptoms associated with the tumor, thereby treating the tumor in the subject. |
申请公布号 |
CA2791702(A1) |
申请公布日期 |
2011.09.15 |
申请号 |
CA20112791702 |
申请日期 |
2011.03.10 |
申请人 |
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES;SRI INTERNATIONAL |
发明人 |
WAINER, IRVING W.;BERNIER, MICHEL;TOLL, LAWRENCE ROBERT;JIMENEZ, LUCITA ARENAS |
分类号 |
A61K31/137;A61P35/00 |
主分类号 |
A61K31/137 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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