发明名称 |
USE OF ERBB3 INHIBITORS IN THE TREATMENT OF TRIPLE NEGATIVE AND BASAL-LIKE BREAST CANCERS |
摘要 |
Provided are methods of suppressing growth of triple negative breast tumors and basal-like breast tumors by contacting tumor cells with an ErbB3 inhibitor, e.g., an anti- ErbB3 antibody. Also provided are methods for treating triple negative breast cancer or basal-like breast cancer in a patient by administering to the patient an ErbB3 inhibitor, e.g., an anti-ErbB3 antibody. The treatment methods can further comprise selecting a patient having a triple negative breast cancer or basal-like breast cancer and then administering an ErbB3 inhibitor to the patient. The treatment methods also can further comprise administering at least one additional anti-cancer agent to the patient in combination with the ErbB3 inhibitor. |
申请公布号 |
WO2011112953(A2) |
申请公布日期 |
2011.09.15 |
申请号 |
WO2011US28129 |
申请日期 |
2011.03.11 |
申请人 |
MERRIMACK PHARMACEUTICALS, INC.;MOYO, VICTOR;GARCIA, GABRIELA |
发明人 |
MOYO, VICTOR;GARCIA, GABRIELA |
分类号 |
A61K39/00 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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