HUMAN CANCER MICRO-RNA EXPRESSION PROFILES PREDICTIVE OF CHEMO-RESPONSE
摘要
Disclosed are identified and successfully targeted microRNAs (miRNAs) associated with human cancer cell line response to a range of anti-cancer agents. The strategy of integrating in vitro miRNA expression and drug sensitivity data not only aid in the characterization of determinants of cytotoxic response, but also in the identification of novel therapeutic targets.
申请公布号
WO2011113030(A2)
申请公布日期
2011.09.15
申请号
WO2011US28238
申请日期
2011.03.11
申请人
H.LEE MOFFITT CANCER CENTER & RESEARCH INSTITUTE;LANCASTER, JOHNATHAN;XIONG, YIN;CHEN, NING