发明名称 |
Substituted, non-coding nucleic acid molecule for therapeutic and prophylactic stimulation of the immune system in humans and higher animals |
摘要 |
Short deoxyribonucleic acid molecules that are partially single-stranded, dumbbell shaped, and covalently closed, which contain one or more unmethylated cytosine guanosine motif (CpG motif) and exhibit immunomodifying effects. Such molecules can be used for immunostimulation applications in humans and vertebrates.
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申请公布号 |
US8017591(B2) |
申请公布日期 |
2011.09.13 |
申请号 |
US20060506766 |
申请日期 |
2006.08.18 |
申请人 |
MOLOGEN AG |
发明人 |
BRZEZICHA BERNADETTE;JUHLS CHRISTIANE;SACK FLORIAN;SCHMIDT MANUEL;WITTIG BURGHARDT;SCHROFF MATTHIAS |
分类号 |
A61K48/00;A61K31/713;A61K38/00;A61K39/00;A61K47/48;C07H21/04;C12N15/117 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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