发明名称 |
LOW-TEMPERATURE COFIRED FLUOROHYDROXYAPATITE CERAMICS FOR RECONSTRUCTION OF BONE DEFECTS |
摘要 |
FIELD: medicine. ^ SUBSTANCE: invention refers to medicine, particularly to calcium-phosphate fluorohydroxyapatite ceramics for bone graft manufacturing and/or defect replacement in various bone pathologies. Making strong FHA is connected with high temperature of ceramic burning. For sintering temperature reduction, a nanodispersed fluorhydroxyapatite powder and an additive of sodium and lithium fluoride system in amount up to 5 wt % are used. When burned, the additive forms a low-temperature melt that promotes liquid-phase sintering at temperatures less than 700C. Besides, the high concentration of fluorine ions leads to FHA stabilisation of ceramics at temperatures 600-700C and prevents formation of the other isomorphic hydroxyapatite modifications. The fine-crystalline structure with crystal size less than 250 nm and porosity less than 5 % and bending strength to 90 MPa allows using the manufactured fluorohydroxyapatite ceramics as strong nonresorbable bone grafts. ^ EFFECT: provided high strength and slow destruction in aqueous mediums observed as ceramic strength loss as a result of chemical corrosion under mechanical pressure. ^ 1 tbl, 1 ex |
申请公布号 |
RU2428206(C1) |
申请公布日期 |
2011.09.10 |
申请号 |
RU20100124155 |
申请日期 |
2010.06.16 |
申请人 |
UCHREZHDENIE ROSSIJSKOJ AKADEMII NAUK INSTITUT METALLURGII I MATERIALOVEDENIJA IM. A.A. BAJKOVA RAN |
发明人 |
SMIRNOV VALERIJ VJACHESLAVOVICH;ANTONOVA OL'GA STANISLAVOVNA;BARINOV SERGEJ MIRONOVICH;TJUT'KOVA JULIJA BORISOVNA |
分类号 |
A61F2/28;A61L27/02;A61L27/12 |
主分类号 |
A61F2/28 |
代理机构 |
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