发明名称 METHOD OF PREVENTING RECURRENCES OF OPIUM ADDICTION
摘要 FIELD: medicine. ^ SUBSTANCE: invention relates to field of medicine, namely to narcology. In order to predict recurrences of opium addiction in patient monthly carried out is incubation of lymphocytes in vitro in two samples: in presence of morphine in dose 10-6 M and in its absence - with further hystochemical staining for 5'-nucleotidase and semi-quantitative evaluation of said staining efficiency in points. Ratio of average points of staining for 5'-nucleotidase in lymphocytes, incubated with morphine and in its absence is calculated by division of first index by second. If said ratio decreases by more than 30% in comparison with the norm, appropriate preventive treatment is administered to patient. ^ EFFECT: method makes it possible to predict recurrences of opium addiction after withdrawal of patients from abstinence syndrome, due to detection of biological marker, anticipating clinical manifestations of recurrence. ^ 1 ex
申请公布号 RU2428123(C1) 申请公布日期 2011.09.10
申请号 RU20100115409 申请日期 2010.04.20
申请人 FEDERAL'NOE GOSUDARSTVENNOE UCHREZHDENIE, NATSIONAL'NYJ NAUCHNYJ TSENTR NARKOLOGII, FEDERAL'NOGO AGENTSTVA PO ZDRAVOOKHRANENIJU I SOTSIAL'NOMU RAZVITIJU 发明人 PANCHENKO LEONID FEDOROVICH;NAUMOVA TAT'JANA ALEKSANDROVNA;NADEZHDIN ALEKSEJ VALENTINOVICH;NASEDKIN ALEKSEJ ALEKSEEVICH
分类号 A61B10/00;G01N1/28 主分类号 A61B10/00
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