发明名称 |
TREATMENT OF BRAIN DERIVED NEUROTROPHIC FACTOR (BDNF) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO BDNF |
摘要 |
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Brain derived neurotrophic factor (BDNF), in particular, by targeting natural antisense polynucleotides of Brain derived neurotrophic factor (BDNF). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of BDNF. |
申请公布号 |
WO2010093904(A9) |
申请公布日期 |
2011.09.09 |
申请号 |
WO2010US24075 |
申请日期 |
2010.02.12 |
申请人 |
OPKO CURNA, LLC;COLLARD, JOSEPH;KHORKOVA SHERMAN, OLGA;COITO, CARLOS |
发明人 |
COLLARD, JOSEPH;KHORKOVA SHERMAN, OLGA;COITO, CARLOS |
分类号 |
A61K48/00;A61K38/16;A61P25/00;A61P25/16;A61P25/28 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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